"How can I tell all the people who have laughed and cried with me through seventy-five years in the theater, all over the world, when I was up and when I was down, and especially now that I am on my own, how can I tell you how much your love for me has gladdened my heart through a wonderful life?"

Returning to work after Kalich's death was especially difficult for Picon because so much of her career as well as her personal life was intricately tied to her husband. Picon was also beginning to experience the effects of a mild case of Bell's Palsy connected with Alzheimer's disease. Nevertheless, at 81 years of age, Picon created and toured with her one-woman show, Hello Molly. The show traced her long and loving relationship with the Yiddish Theater and gave her an opportunity to remain connected to her beloved audiences.